Hey RC, I've done some tinkering around. Try the German patches, they're super easy to unpatch so it won't hurt to try.
For YR 1.001 the German patch seems to work fine for mouse issues - now the only problem that exists is with loading and videos, the only solid response is from this forum:
The issue being that resizing totally breaks the fullscreen rendering.
If you're still having issues with the mouse, try disabling acceleration from your mouse software, and changing it only from Windows mouse settings?
As for the game speed, maybe try this in the .ini:
[Options]
GameSpeed=6
GameSpeed=3
GameSpeed=1
Where 6 is fastest and 3 is normal; 1 is probably lowest, haven't tested because I don't hate myself.
I still maintain that for YR multiplayer the CNCNET patch is probably the greatest thing since sliced bread, however for singleplayer stick to vanilla 1.001.
If all else fails then hit me up via PM - let's set up a troubleshooting chat.